DCMud has a nice post about the "Arts District" in Hyattsville, just across the DC line. EYA is developing several parcels on both sides of Route 1. According to the blog post, the economy has slowed progress, but people are gradualy moving into the live/work spaces. Read more here HERE.
Ultimately Rhode Island Ave could be an extensive art corridor, running through NE DC all the way out to the University of Maryland.